| Primary non-Hodgkin's lymphomas of the central nervous system. Still more questions than answers in the treatment? | |
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MedLine Citation:
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PMID: 17592682 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The optimal treatment of primary non-Hodgkin"s lymphomas of the central nervous system is still under discussion. Systemic treatment is compromised by the blood-brain barrier which is impermeable to several cytostatic agents. For several years, the standard treatment has been methotrexate-based chemotherapy followed by CNS-radiotherapy. However, this combination therapy may be complicated by later neurotoxicity. Intensive chemotherapy followed by autologous stem-cell transplantation is a new promising treatment approach without increased CNS-toxicity. |
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Authors:
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Per Boye Hansen; Morten Krogh Jensen |
Publication Detail:
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Type: English Abstract; Journal Article; Review |
Journal Detail:
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Title: Ugeskrift for laeger Volume: 169 ISSN: 1603-6824 ISO Abbreviation: Ugeskr. Laeg. Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-06-26 Completed Date: 2007-07-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0141730 Medline TA: Ugeskr Laeger Country: Denmark |
Other Details:
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Languages: dan Pagination: 2187-9 Citation Subset: IM |
Affiliation:
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Herlev Hospital, Medicinsk Haematologisk Afdeling L, Herlev. peboha01@herlevhosp.kbhamt.dk |
Vernacular Title:
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Primaere non-Hodgkin-lymfomer i centralnervesystemet. Stadig flere spørgsmål end svar i behandlingen? |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Agents
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therapeutic use Brain Neoplasms / drug therapy, radiotherapy, therapy* Combined Modality Therapy Humans Lymphoma, B-Cell / drug therapy, radiotherapy, therapy Lymphoma, Non-Hodgkin / drug therapy, radiotherapy, therapy* Lymphoma, T-Cell / drug therapy, radiotherapy, therapy Stem Cell Transplantation Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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