Document Detail

Primary middle ear Epstein-Barr virus-related lymphoepithelial carcinoma: case reports and systematic review.
MedLine Citation:
PMID:  19877237     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES/HYPOTHESIS: To report two cases of primary lymphoepithelial carcinoma in the middle ear and to determine the optimal treatment for such lesions. STUDY DESIGN/METHODS: Case reports and a systematic review of the literature. RESULTS: Primary lymphoepithelial carcinoma in the middle ear is an exceptionally rare condition with only two other cases reported in the literature. There appears to be an association with Epstein-Barr virus infection and in those patients originating from the Guangdong province of China, much as is the case for similar lesions found in the nasopharynx. Piecemeal rather than en bloc excision, in combination with adjuvant radiotherapy, appears to adequately control the disease. CONCLUSIONS: Primary lymphoepithelial carcinoma of the middle ear is a rare lesion, which when treated has a good prognosis.
Matthew P A Clark; Brian D Westerberg; Kenneth W Berean
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Laryngoscope     Volume:  120     ISSN:  1531-4995     ISO Abbreviation:  Laryngoscope     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-24     Completed Date:  2010-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  United States    
Other Details:
Languages:  eng     Pagination:  172-7     Citation Subset:  IM    
Division of Otolaryngology, Vancouver General Hospital and University of British Columbia, British Columbia, Canada.
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MeSH Terms
Carcinoma, Squamous Cell / etiology*,  surgery*
Ear Neoplasms / etiology*,  surgery*
Ear, Middle
Epstein-Barr Virus Infections / complications*
Middle Aged
Radiotherapy, Adjuvant

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