Document Detail


Primary microcephaly in two children born to mothers with complicated appendicitis or late appendectomy during pregnancy.
MedLine Citation:
PMID:  19235832     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The possible association between maternal appendicitis/appendectomy during pregnancy and congenital abnormalities in the offspring was studied. CASES: Two cases with primary microcephaly were born to mothers who had complicated appendicitis owing to the delay of appendectomy resulting in abscess/peritonitis associated with septicemia and fever in the second trimester of pregnancy. CONCLUSIONS: Delay in surgical intervention of appendicitis in pregnancy can result in maternal morbidity that may be associated with primary microcephaly in the offspring.
Authors:
Nándor Acs; Ferenc Bánhidy; Andrew E Czeizel
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Birth defects research. Part A, Clinical and molecular teratology     Volume:  85     ISSN:  1542-0760     ISO Abbreviation:  Birth Defects Res. Part A Clin. Mol. Teratol.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-14     Completed Date:  2009-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101155107     Medline TA:  Birth Defects Res A Clin Mol Teratol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  655-6     Citation Subset:  IM    
Affiliation:
Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary.
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MeSH Terms
Descriptor/Qualifier:
Adult
Appendectomy / adverse effects*
Appendicitis / complications*,  surgery
Female
Humans
Infant, Newborn
Microcephaly / etiology*
Pregnancy
Pregnancy Complications / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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