| Primary meningeal rhabdomyosarcoma. | |
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MedLine Citation:
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PMID: 21772793 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Primary meningeal rhabdomyosarcoma is a rare primary brain malignancy, with scant case reports. While most reports of primary intracranial rhabdomyosarcoma occur in pediatric patients, a handful of cases in adult patients have been reported in the medical literature. We report the case of a 44-year-old male who developed primary meningeal rhabdomyosarcoma. After developing episodes of right lower extremity weakness, word finding difficulty, and headaches, a brain magnetic resonance imaging (MRI) demonstrated a vertex lesion with radiographic appearance of a meningeal-derived tumor. Subtotal surgical resection was performed due to sagittal sinus invasion and initial pathology was interpreted as an anaplastic meningioma. Re-review of pathology demonstrated rhabdomyosarcoma negative for alveolar translocation t(2;13). Staging studies revealed no evidence of disseminated disease. He was treated with stereotactic radiotherapy with concurrent temozolamide to be followed by vincristine, actinomycin-D, and cyclophosphamide (VAC) systemic therapy. |
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Authors:
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Manisha Palta; Richard F Riedel; James J Vredenburgh; Thomas J Cummings; Scott Green; Zheng Chang; John P Kirkpatrick |
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Publication Detail:
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Type: Journal Article Date: 2011-06-23 |
Journal Detail:
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Title: Sarcoma Volume: 2011 ISSN: 1369-1643 ISO Abbreviation: Sarcoma Publication Date: 2011 |
Date Detail:
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Created Date: 2011-07-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9709257 Medline TA: Sarcoma Country: Egypt |
Other Details:
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Languages: eng Pagination: 312802 Citation Subset: - |
Affiliation:
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Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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