Document Detail

Primary melanoma of skin of the breast region.
MedLine Citation:
PMID:  831633     Owner:  NLM     Status:  MEDLINE    
Primary melanoma of skin of the breast region accounted for less than 5% of all malignant melanomas. During a two-year period, 12 patients were seen with these unique lesions. It appears that wide excision and prophylactic lymphadenectomy, including radical mastectomy, gave the best long-term local and regional control. Dissection of the internal mammary nodes did not seem to be beneficial. Pertinent literatures emphasizing several important pathological factors which correlate with higher incidence of metastases to the regional lymph nodes are reviewed. A rational therapeutic approach, synthesizing above information and incorporating postoperative adjuvant immunotherapy, is suggested.
Y T Lee; F C Sparks; D L Morton
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Annals of surgery     Volume:  185     ISSN:  0003-4932     ISO Abbreviation:  Ann. Surg.     Publication Date:  1977 Jan 
Date Detail:
Created Date:  1977-02-26     Completed Date:  1977-02-26     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372354     Medline TA:  Ann Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  17-22     Citation Subset:  AIM; IM    
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MeSH Terms
Breast Neoplasms / surgery*
Lymph Node Excision
Melanoma / surgery*
Middle Aged
Neoplasm Metastasis
Neoplasm Recurrence, Local
Skin Neoplasms / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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