Document Detail

Primary malignant melanoma of the vulva associated with pregnancy: clinical, light and electron microscopic observations.
MedLine Citation:
PMID:  6663148     Owner:  NLM     Status:  MEDLINE    
A case of primary malignant melanoma of the vulva associated with pregnancy in a 31-year-old patient is reported. The primary tumor was first found at week 14 of pregnancy and biopsied on delivery at week 41 of pregnancy. Microscopically, the depth of invasion was Level V. Radical vulvectomy and bilateral inguino-femoral lymphadenectomy were performed and the right inguinal lymph node was positive for metastatic tumor. Chemoimmunotherapy with DTIC, ACNU, VCR and OK432 was undertaken as treatment for this malignant melanoma. Moreover, a comparison of scanning and transmission electron microscopic studies of the original tumor was carried out. This patient is now living 23 months after diagnosis without clinical evidence of recurrence.
M Munemura; S Inoue; Y Rin; S Fukuda; M Maeyama; T Iwamasa
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Nihon Sanka Fujinka Gakkai zasshi     Volume:  35     ISSN:  0300-9165     ISO Abbreviation:  Nippon Sanka Fujinka Gakkai Zasshi     Publication Date:  1983 Dec 
Date Detail:
Created Date:  1984-03-23     Completed Date:  1984-03-23     Revised Date:  2011-07-29    
Medline Journal Info:
Nlm Unique ID:  7505749     Medline TA:  Nihon Sanka Fujinka Gakkai Zasshi     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  2404-8     Citation Subset:  IM    
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MeSH Terms
Lymphatic Metastasis
Melanoma / pathology,  ultrastructure*
Microscopy, Electron, Scanning
Pregnancy Complications, Neoplastic / pathology,  ultrastructure*
Vulvar Neoplasms / pathology,  ultrastructure*

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