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Primary malignant fibrous histiocytoma of spleen with spontaneous rupture: a case report and literature review.
MedLine Citation:
PMID:  20354829     Owner:  NLM     Status:  In-Data-Review    
Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma that mainly occurs in the lower and upper extremities, trunk and retroperitoneum. However, primary MFH of the spleen is especially rare. Only 11 cases of splenic MFH have been reported in the English literature. In this report, we describe a 35-year-old man who was found to have a large accumulation of free fluid in the abdominal cavity and a tumor mass 6 cm in diameter with rupture within the spleen by the abdominal ultrasonography. A splenectomy was performed and the histological diagnosis was malignant fibrous histiocytoma. The patient died 7 months after the operation as a result of generalized metastasis. Compared with the 11 previously documented patients of splenic MFH, our patient is the youngest and the first case with spontaneous rupture, which makes our case exceedingly rare. A literature review of primary MFH of spleen is also provided.
Liang He; Hao Zhang; Xuan Li; Jianping Zhou; Ming Dong
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Publication Detail:
Type:  Journal Article     Date:  2010-03-31
Journal Detail:
Title:  Medical oncology (Northwood, London, England)     Volume:  28     ISSN:  1559-131X     ISO Abbreviation:  Med. Oncol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9435512     Medline TA:  Med Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  397-400     Citation Subset:  IM    
Department of General Surgery, The First Hospital of China Medical University, No. 155, Nanjing Bei Street, 110001, Heping District, Shenyang, Liaoning, China.
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