Document Detail


Primary lymphoblastic B-cell lymphoma of the cranial dura mater: a case report and review of the literature.
MedLine Citation:
PMID:  16334908     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primary lymphomas of the cranial dura mater are rare. Mucosa-associated lymphoid tissue extranodal marginal zone lymphomas are the most common subtype of non-Hodgkin's lymphomas that present as primary cranial dura tumors. A 33 year-old male presented with a 3-month history of a growing lump in the right frontal area. Neuroimaging studies demonstrated an extra-axial, broad-based mass with a dural tail in the right frontal bone convexity. Biopsy led to the diagnosis of localized dural precursor B-cell lymphoblastic lymphoma. The patient was treated with a combination of chemotherapy and radiotherapy, achieving durable disease-free survival. This is the first report of precursor B-cell lymphoblastic lymphoma of dura mater. A review of the literature on primary lymphomas of cranial dura mater is presented. Primary lymphomas of the cranial dura mater are rare. Mucosa-associated lymphoid tissue extranodal marginal zone lymphomas are the most common subtype of non-Hodgkin's lymphomas that present as primary cranial dura tumors. A 33 year-old male presented with a 3-month history of a growing lump in the right frontal area. Neuroimaging studies demonstrated an extra-axial, broad-based mass with a dural tail in the right frontal bone convexity. Biopsy led to the diagnosis of localized dural precursor B-cell lymphoblastic lymphoma. The patient was treated with a combination of chemotherapy and radiotherapy, achieving durable disease-free survival. This is the first report of precursor B-cell lymphoblastic lymphoma of dura mater. A review of the literature on primary lymphomas of cranial dura mater is presented.
Authors:
Sakher Abdullah; Daniel Morgensztern; Manuel F Rosado; Izidore S Lossos
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Leukemia & lymphoma     Volume:  46     ISSN:  1042-8194     ISO Abbreviation:  Leuk. Lymphoma     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-12-08     Completed Date:  2006-01-12     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  9007422     Medline TA:  Leuk Lymphoma     Country:  England    
Other Details:
Languages:  eng     Pagination:  1651-7     Citation Subset:  IM    
Affiliation:
Department of Medicine, Division of Hematology and Oncology, University of Miami/Sylvester Cancer Center, Miami, FL 331396, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antineoplastic Agents / therapeutic use
Central Nervous System Neoplasms / diagnosis,  pathology*,  therapy
Disease-Free Survival
Dura Mater / pathology*
Humans
Immunophenotyping
Lymphoma, B-Cell
Magnetic Resonance Imaging
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Radiotherapy, Adjuvant
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

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