Document Detail


Primary lymphatic dysplasia in children: chylothorax, chylous ascites, and generalized lymphatic dysplasia.
MedLine Citation:
PMID:  3769996     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primary lymphatic "dysplasia", a congenital maldevelopment, interferes with function of the lymphatic system and causes effusion of chyle or lymph into the limbs and pleural or peritoneal cavity. Between 1955 and 1982, 38 Mayo Clinic patients were found to have a chylous effusion or dysplasia of the lymphatic system. In 22, the condition was secondary to surgery or other medical problems and in 16 it was primary. These cases were separated into three categories: chylothorax, chylous ascites, and generalized lymphatic dysplasia. Conservative therapy, such as a restricted fat diet or total parenteral nutrition with repeated thoracentesis or paracentesis, was effective in the children with isolated abnormalities of the lymphatic system (75% resolution rate, no deaths). All five children with documented generalized dysplasia reported in the literature had died; of the three reported here, one has died and two have become progressively worse.
Authors:
D M Smeltzer; G B Stickler; R E Fleming
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  145     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1986 Sep 
Date Detail:
Created Date:  1986-12-11     Completed Date:  1986-12-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  286-92     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Child, Preschool
Chylothorax / congenital,  diagnosis*,  pathology
Chylous Ascites / congenital,  diagnosis*,  pathology
Female
Humans
Infant
Infant, Newborn
Lymphatic Diseases / congenital,  diagnosis*,  pathology
Male

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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