| "Primary" leptomeningeal medulloblastoma. | |
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MedLine Citation:
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PMID: 19695677 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the case of an 8-year-old boy who presented with a 2-month history of headaches and mild visual impairment and was found to have a medulloblastoma with primary leptomeningeal involvement. No mass lesion was found on imaging studies, during subsequent intraoperative surgical inspection or at autopsy. The pathologic findings were first documented on cerebrospinal fluid cytologic examination and biopsy of the cerebellum and were later confirmed at necropsy. To our knowledge, this is the third reported case of medulloblastoma identified with primary leptomeningeal involvement without a cerebellar mass and the first such case with documented autopsy findings. |
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Authors:
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Rupal I Mehta; Aaron R Cutler; Joseph L Lasky; William H Yong; Jason T Lerner; Brandon K Hirota; Noriko Salamon; Gary W Mathern; Harry V Vinters |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-08-19 |
Journal Detail:
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Title: Human pathology Volume: 40 ISSN: 1532-8392 ISO Abbreviation: Hum. Pathol. Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-10-19 Completed Date: 2009-11-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9421547 Medline TA: Hum Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 1661-5 Citation Subset: IM |
Affiliation:
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Department of Pathology and Laboratory Medicine (Section of Neuropathology), University of California, Los Angeles, CA 90024, USA. rmehta@mednet.ucla.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use Cerebellar Neoplasms / pathology*, therapy Child Combined Modality Therapy Fatal Outcome Humans Male Medulloblastoma / pathology*, therapy Meningeal Neoplasms / pathology*, therapy Neurosurgical Procedures |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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