Document Detail

Primary leiomyosarcoma of the testis. A case report.
MedLine Citation:
PMID:  20592368     Owner:  NLM     Status:  MEDLINE    
Primary leiomyosarcoma of the testis is an extremely rare disease entity of the genito-urinary tract. Although its clinical presentation does not seem to differ from that of other testicular malignancies, the clinical stage with which patients have been treated, as reported in contemporary literature, has always been stage 1. Diagnosis is achieved by combining histologic and immunohistochemical findings. Histologic findings refer to the presence of a spindle cell component with nuclear pleomorphism, while immunohistochemical findings refer to its reaction to specific antibodies. Although the number of reported cases is not significant and the clinical and biological behaviour of these tumors are very hard to predict, we demonstrate that radical orchidectomy followed by surveillance appears to be the treatment of choice. Retroperitoneal lymphadenectomy, radiotherapy and chemotherapy do not seem to have any place in the treatment of this type of malignancy.
Apostolos P Labanaris; Vahudin Zugor; Robert Smiszek; Reinhold Nützel; Reinhard Kühn
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anticancer research     Volume:  30     ISSN:  1791-7530     ISO Abbreviation:  Anticancer Res.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-07-01     Completed Date:  2010-07-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8102988     Medline TA:  Anticancer Res     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  1725-6     Citation Subset:  IM    
Department of Urology, Martha Maria Medical Center, Nürnberg, Germany.
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MeSH Terms
Antineoplastic Agents / pharmacology
Cell Nucleus / metabolism
Immunohistochemistry / methods
Leiomyosarcoma / diagnosis*,  pathology*
Medical Oncology / methods
Mitotic Spindle Apparatus / metabolism
Testicular Neoplasms / diagnosis*,  pathology*
Testis / pathology
Reg. No./Substance:
0/Antineoplastic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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