Document Detail


Primary leiomyosarcoma of the ovary in a perimenarchal female.
MedLine Citation:
PMID:  8462904     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of primary leiomyosarcoma of the ovary in a perimenarchal female is presented. Previous to this report, ovarian leiomyosarcoma was thought to arise predominantly in postmenopausal women and, indeed, this is the first reported case in a pubertal adolescent. The sarcoma was associated with bilateral cellular ovarian leiomyomas, suggesting malignant degeneration of such tumors. After complete resection, the patient is alive without evidence of recurrent disease 20 months after diagnosis. A review of the literature suggests that chemoradiation is of unproven benefit and aggressive surgical management is recommended.
Authors:
B J Monk; R Nieberg; J S Berek
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Gynecologic oncology     Volume:  48     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-04-30     Completed Date:  1993-04-30     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  389-93     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Jonnson Comprehensive Cancer Center, University of California, Los Angeles 90024.
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MeSH Terms
Descriptor/Qualifier:
Cerebellar Neoplasms / complications
Child
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 15
Chromosomes, Human, Pair 22
Female
Humans
Leiomyosarcoma* / complications,  genetics,  pathology,  surgery
Medulloblastoma / complications
Menarche
Ovarian Neoplasms* / complications,  genetics,  pathology,  surgery
Translocation, Genetic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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