Document Detail


Primary laryngeal lymphoma: case report.
MedLine Citation:
PMID:  16579200     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Extranodal laryngeal lymphoma is extremely rare. We report a case of primary laryngeal lymphoma in a 76-year-old man who had presented with a 7-week history of progressive hoarseness. Laryngoscopy revealed asymmetry of the right false vocal fold. Pathology of a deep biopsy specimen identified a malignant, diffuse, CD20-positive, B-cell lymphoma. The stage IE lymphoma completely resolved after treatment with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) and rituximab. Despite its relative rarity, the consequences of a missed diagnosis warrant vigilance for this type of laryngeal tumor.
Authors:
Ronnie Word; Andrew C Urquhart; Victor S Ejercito
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Ear, nose, & throat journal     Volume:  85     ISSN:  0145-5613     ISO Abbreviation:  Ear Nose Throat J     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-04-03     Completed Date:  2007-04-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7701817     Medline TA:  Ear Nose Throat J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  109-11     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Marshfield Clinic, Marshfield, WI 54449, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biopsy
Cyclophosphamide / therapeutic use
Doxorubicin / therapeutic use
Hoarseness
Humans
Laryngeal Neoplasms / diagnosis*,  drug therapy*
Laryngoscopy
Lymphoma / diagnosis*,  drug therapy*
Male
Prednisone / therapeutic use
Tomography, X-Ray Computed
Treatment Outcome
Vincristine / therapeutic use
Vocal Cords / pathology
Chemical
Reg. No./Substance:
0/CHOP protocol; 23214-92-8/Doxorubicin; 50-18-0/Cyclophosphamide; 53-03-2/Prednisone; 57-22-7/Vincristine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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