| Primary laryngeal lymphoma: report of 3 cases and review of the literature. | |
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MedLine Citation:
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PMID: 19378323 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Extranodal lymphomas limited to the larynx are rare, accounting for less than 1% of all laryngeal neoplasms. The aim of this study was to report the experience of our department in the management of these aggressive lesions, as they require special diagnostic and therapeutic attention. METHODS: The case records of 3 patients with the diagnosis of lymphoma involving the larynx were retrospectively reviewed. RESULTS: The histopathological diagnosis revealed 1 case of marginal zone lymphoma mucosa-associated lymphoid tissue type, 1 case of T-lymphoblastic lymphoma, and 1 case of a rare coexistence of in situ squamous cell carcinoma with an isolated intravascular (angioimmunoblastic) lymphoma of peripheral T-cell origin. Details of the presentation, diagnostic procedures, treatment, and outcome of these patients were presented. CONCLUSIONS: Primary laryngeal lymphoma is a rare entity. Early symptoms are subtle and nonspecific, and confirmation of the diagnosis is often difficult. Because of the rarity of this tumor type, the optimal management remains controversial and it seems that should be managed not as a distinct disease entity but as an unusual presentation of non-Hodgkin lymphoma, according to the recent treatment trends. |
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Authors:
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Konstantinos Markou; John Goudakos; John Constantinidis; Ioannis Kostopoulos; Victor Vital; Angelos Nikolaou |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Head & neck Volume: 32 ISSN: 1097-0347 ISO Abbreviation: Head Neck Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-17 Completed Date: 2010-06-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8902541 Medline TA: Head Neck Country: United States |
Other Details:
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Languages: eng Pagination: 541-9 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology-Head and Neck Surgery, ENT Department, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Antineoplastic Combined Chemotherapy Protocols / therapeutic use Biopsy, Needle Combined Modality Therapy Fatal Outcome Humans Immunohistochemistry Laryngeal Neoplasms / diagnosis, pathology*, therapy Lymphoma, B-Cell, Marginal Zone / diagnosis, pathology*, therapy Lymphoma, Non-Hodgkin / diagnosis, pathology*, therapy Male Middle Aged Neoplasm Staging Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis, pathology*, therapy Prognosis Radiotherapy, High-Energy / methods Risk Assessment Tracheotomy / methods |
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