Document Detail

Primary intraorbital extraocular primitive neuroectodermal (neuroepithelial) tumour.
MedLine Citation:
PMID:  3718918     Owner:  NLM     Status:  MEDLINE    
A case is reported of primary primitive neuroectodermal (neuroepithelial) tumour occurring in the right orbit of a 52-year-old man. The intraorbital extraocular location is unique for this kind of neoplasm. The malignant tumour was differentiated into primitive neuroepithelial, ependymal, and oligodendroglial cells. The neuroglia was identified by localisation of cytoplasmic glial fibrillary acidic protein. It is suggested that this primary intraorbital, extraocular, primitive neuroectodermal tumour with neuroglial differentiation is akin to the primitive neuroectodermal tumours of the neuraxis, including the cerebellar medulloblastomas, and to some peripheral nerve tumours known as malignant neuroepitheliomas, malignant ependymomas, and neuroblastomas. The ectomesenchymal remnant of the neural crest or ectopic neuroepithelium or both may have been the origin of the present tumour. Differentiation of the neuroectodermal component of the neural crest or heterotopic neuroepithelium or both would create a primitive neuroectodermal tumour with diverse neuroglial elements.
S Shuangshoti; W Menakanit; W Changwaivit; N Suwanwela
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  70     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  1986 Jul 
Date Detail:
Created Date:  1986-08-20     Completed Date:  1986-08-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  543-8     Citation Subset:  IM    
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MeSH Terms
Middle Aged
Neuroectodermal Tumors, Primitive, Peripheral / pathology*,  radiography
Orbital Neoplasms / pathology*,  radiography
Tomography, X-Ray Computed

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