Document Detail


Primary intracranial leiomyosarcoma in an HIV-infected patient.
MedLine Citation:
PMID:  20676716     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primary intracranial leiomyosarcomas are rare tumors arising from the mesenchymal cells of the dura matter or the cerebral blood vessels. Only 14 cases of primary intracranial leiomyosarcoma are reported in the literature. We report a case of primary intracranial leiomyosarcoma in an human immunodeficiency virus-positive patient with a CD4 count of 14 cells/μL. Additionally, in-situ hybridization of Epstein-Barr virus (EBV) early RNA stained sections highlighted the tumor cells, consistent with the presence of EBV. Review of the literature strongly suggests an association between AIDS, EBV, and primary intracranial leiomyosarcoma. Given the paucity of information in the literature, we review possible chemotherapeutic agents for treatment of primary intracranial leiomyosarcoma in patients refractory to surgical resection and radiation therapy.
Authors:
Shanthi Sivendran; Claudia Irene Vidal; Myra F Barginear
Related Documents :
6751106 - Gliomatosis peritonei. report of two cases and review of literature.
6603116 - Leiomyomatous lung lesions: a proposed classification.
6837836 - Leiomyosarcoma of the broad ligament. a case report and literature review with follow-up.
11853046 - Red degeneration of a leiomyoma masquerading as retained products of conception.
25333016 - Pulmonary carcinosarcoma with heterologous component: report of two cases with literatu...
24574786 - Family case of achalasia cardia: case report and review of literature.
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2010-07-30
Journal Detail:
Title:  International journal of clinical oncology     Volume:  16     ISSN:  1437-7772     ISO Abbreviation:  Int. J. Clin. Oncol.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-10     Completed Date:  2011-05-24     Revised Date:  2012-12-13    
Medline Journal Info:
Nlm Unique ID:  9616295     Medline TA:  Int J Clin Oncol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  63-6     Citation Subset:  IM    
Affiliation:
Tisch Cancer Institute, The Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1079, New York, NY 10029, USA, shanthi.sivendran@mssm.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acquired Immunodeficiency Syndrome / complications*,  drug therapy
Adult
Anti-Retroviral Agents / therapeutic use
Brain Neoplasms / pathology*,  surgery,  virology*
Epstein-Barr Virus Infections / drug therapy,  pathology*,  virology*
Herpesvirus 4, Human / isolation & purification*
Humans
Leiomyosarcoma / pathology*,  surgery,  virology*
Magnetic Resonance Imaging
Male
Chemical
Reg. No./Substance:
0/Anti-Retroviral Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Regulation of barley miRNAs upon dehydration stress correlated with target gene expression.
Next Document:  The use of fibrin glue in the treatment of complex perianal fistulae: a case report.