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Primary intracerebral Hodgkin lymphoma with recurrence.
MedLine Citation:
PMID:  21329616     Owner:  NLM     Status:  Publisher    
Objective: To report a case of primary intracerebral Hodgkin lymphoma with disease recurrence. Methods: Case report and review of the literature. Results: A 58-year-old immunocompetent male presented with aphasia. Neuroimaging revealed a left temporal lobe lesion. A craniotomy and resection were performed, and the diagnosis of classical Hodgkin lymphoma was made. Systemic work-up for lymphoma was negative. Postoperatively, the patient was treated with whole brain irradiation. 14 months later, the patient developed an enhancing lesion in his pons and received combination chemotherapy and radiation therapy. Repeat imaging demonstrated leptomeningeal enhancement and multiple lesions throughout the cerebral hemispheres, cerebellum and brainstem. Comment: We report what appears to be the first case of a patient with aggressive primary intracerebral Hodgkin lymphoma with disease recurrence.
W -C Foo; A Desjardins; T J Cummings
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Publication Detail:
Journal Detail:
Title:  Clinical neuropathology     Volume:  30     ISSN:  0722-5091     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-2-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214420     Medline TA:  Clin Neuropathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  75-79     Citation Subset:  -    
Departments of 1Pathology and 2Neurology, Duke University Medical Center, Durham, NC, USA.
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