| Primary hyperparathyroidism presenting with severe hypertension in a middle aged Nigerian--a case report. | |
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MedLine Citation:
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PMID: 18408787 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To draw attention to primary hyperparathyroidism as a cause of severe hypertension. RESULTS: A 47 year old Nigerian male presented with headache, occasional blurring of vision and dyspnoea on mild exertion of 2/12 duration. He had been troubled by painful osteoarthritis of the knees for 2 years for which he was taking NSAIDs. He was found to be severely hypertensive, BP 210/130mmHg and had bilateral knee crepitus. BP was resistant to control on Nifedipine R and Moduretic. Serum urea, creatinine, uric acid were normal but there was hyperacalcaemia and hyperchloraemia. Haematological indices, urinalysis, microscopy and culture of urine were normal. Parathyroid hormone level was raised. A parathyroid MIBI scan study showed an extensive area of significance towards the inferior pole of the right lobe of thyroid medially with a second area of very low significance medial to the left pole. These findings indicated the presence of a right inferior parathyroid adenoma. He had parathyroid surgery and a large adenoma in the right inferior gland and a smaller left inferior gland were removed and confirmed histologically. Corrected calcium and parathyroid hormone levels dropped to normal, and the BP was easily controlled with Lisinopril 5mg daily subsequently. He is not currently on antihypertensive medication two years post surgery. CONCLUSION: This case highlights the need for thorough investigation of cases of hypertension to exclude specifically secondary causes, which in some cases may be endocrine in origin and may easily be corrected. |
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Authors:
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F H Puepet; E I Agaba; E K Chuhwak; S O Ugoya |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Nigerian postgraduate medical journal Volume: 15 ISSN: 1117-1936 ISO Abbreviation: Niger Postgrad Med J Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-04-14 Completed Date: 2008-06-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9613595 Medline TA: Niger Postgrad Med J Country: Nigeria |
Other Details:
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Languages: eng Pagination: 58-60 Citation Subset: IM |
Affiliation:
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Endocrine and Metabolic Unit, Department of Medicine Jos University Teaching Hospital Jos P.M.B 2076 Jos, Plateau State, Nigeria. puepetfh@yahoo.co.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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diagnosis,
surgery Antihypertensive Agents / therapeutic use Humans Hyperparathyroidism, Primary / diagnosis*, etiology* Hypertension / complications*, drug therapy Lisinopril / therapeutic use Male Middle Aged Nigeria Osteoarthritis, Knee / complications Parathyroid Neoplasms / diagnosis, surgery Parathyroidectomy |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents; 83915-83-7/Lisinopril |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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