Document Detail

Primary hyperparathyroidism and pregnancy.
MedLine Citation:
PMID:  11533747     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The coexistence of primary hyper-parathyroidism and pregnancy is very rare worldwide. It carries serious complications to the mother and fetus, therefore, early diagnosis and management is of paramount importance. METHODS: Over a period of 16 years from 1982-1997, 24 patients with primary hyperparathyroidism were identified from the central diagnostic index data base of King Khalid University Hospital. Out of these, only 3 women with primary hyperparathyroidism complicating pregnancy were identified. RESULTS: All 3 women were in the fourth decade. Two of them had coexisting vitamin D deficiency with initially normal serum calcium and were misdiagnosed as cases of osteomalacia while the third had very high serum calcium on first presentation. A single parathyroid adenoma was identified in all 3 patients with 2 undergoing surgical removal of the adenoma. The third patient unfortunately had an abortion. The babies of the first 2 patients were born healthy with no complications. CONCLUSION: Primary hyperparathyridism, even though rare in pregnancy, carries risks to the mother and fetus and therefore early screening for asymptomatic hyper-parathyroidism in all women of childbearing age and in the early antenatal period of pregnant women is recommended.
M A Fouda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Saudi medical journal     Volume:  21     ISSN:  0379-5284     ISO Abbreviation:  Saudi Med J     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2001-09-04     Completed Date:  2001-10-11     Revised Date:  2008-06-23    
Medline Journal Info:
Nlm Unique ID:  7909441     Medline TA:  Saudi Med J     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  31-5     Citation Subset:  IM    
Department of Medicine, King Khalid University Hospital, PO Box 2925, Riyadh 11461, Kingdom of Saudi Arabia.
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MeSH Terms
Adenoma / complications
Age Distribution
Calcium / blood
Hospitals, Teaching
Hyperparathyroidism / blood,  complications,  diagnosis*,  epidemiology,  etiology,  therapy*
Mass Screening
Parathyroid Hormone / blood
Parathyroid Neoplasms / complications
Pregnancy Complications / blood,  diagnosis*,  epidemiology,  etiology,  therapy*
Pregnancy Outcome / epidemiology
Prenatal Care
Risk Factors
Saudi Arabia / epidemiology
Reg. No./Substance:
0/Parathyroid Hormone; 7440-70-2/Calcium
Comment In:
Saudi Med J. 2000 Jul;21(7):696; author reply 697   [PMID:  17695669 ]
Saudi Med J. 2000 Jul;21(7):695; author reply 697   [PMID:  11500742 ]

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