Document Detail


Primary hyperparathyroidism and the gastrointestinal tract.
MedLine Citation:
PMID:  7466439     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine the frequency of gastrointestinal symptoms in primary hyperparathyroidism, we retrospectively analyzed 100 consecutive patients seen at Emory University Hospital from Jan 1, 1977 through March 1, 1979. At the time of diagnosis, 28 patients complained of nausea, 19 of vomiting, 29 of abdominal pain, and 33 of constipation. One patient presented with acute pancreatitis and 14 had ulcer disease (two gastric and 12 duodenal ulcers). Hypercalcemia increases gastric acid secretion and may account for associated ulcer disease and the ulcer-like pain in primary hyperparathyroidism. The mechanisms causing the other gastrointestinal symptoms in hypercalcemia remain to be elucidated. These symptoms abate on correction of hyperparathyroidism.
Authors:
E C Gardner; T Hersh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  74     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1981 Feb 
Date Detail:
Created Date:  1981-04-13     Completed Date:  1981-04-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  197-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Constipation / etiology
Female
Gastrins / secretion
Gastrointestinal Diseases / etiology*
Humans
Hypercalcemia / complications
Hyperparathyroidism / complications*
Male
Pancreatitis / etiology
Peptic Ulcer / etiology
Chemical
Reg. No./Substance:
0/Gastrins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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