| Primary hyperparathyroidism: changes on biochemical and hormonal profile related to pregnancy. | |
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MedLine Citation:
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PMID: 2754184 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A woman with mild asymptomatic hypercalcemia due to primary hyperparathyroidism became pregnant and her serum calcium normalized while her hypophosphatemia worsered. The PTH was low normal, but her urinary cAMP was elevated. In the second trimester of pregnancy a parathyroid adenoma was removed. After surgery, a transient hypocalcemia that normalized ten days later, a partial recovery of hypophosphatemia, and a 40% reduction of the elevated urinary cAMP excretion were observed. Pregnancy continued uneventful and a normal newborn was delivered. This case demonstrates the diagnostic difficulties posed by primary hyperparathyroidism during pregnancy, derived from inapparent changes in serum calcium and PTH. However, phosphorus and urinary cAMP deviations are significant constituting the basis for a correct diagnosis. |
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Authors:
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J M Lopez; C B Fardella |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of endocrinological investigation Volume: 12 ISSN: 0391-4097 ISO Abbreviation: J. Endocrinol. Invest. Publication Date: 1989 Feb |
Date Detail:
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Created Date: 1989-09-07 Completed Date: 1989-09-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7806594 Medline TA: J Endocrinol Invest Country: ITALY |
Other Details:
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Languages: eng Pagination: 127-9 Citation Subset: IM |
Affiliation:
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Department of Endocrinology, Metabolism and Nutrition, Pontificia Universidad Catolica de Chile, Santiago. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
/
blood,
surgery Adult Calcium / blood Female Humans Hyperparathyroidism / blood* Parathyroid Neoplasms / blood, surgery Phosphates / blood Pregnancy Pregnancy Complications / blood* Pregnancy Complications, Neoplastic / blood, surgery |
| Chemical | |
Reg. No./Substance:
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0/Phosphates; 7440-70-2/Calcium |
| Comments/Corrections | |
Comment In:
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J Endocrinol Invest. 1990 Feb;13(2):195
[PMID:
2158508
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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