Document Detail

Primary hyperaldosteronism--diagnostic approach and management.
MedLine Citation:
PMID:  8300455     Owner:  NLM     Status:  MEDLINE    
Primary hyperaldosteronism was detected in 1% of patients evaluated for secondary hypertension in a referral hospital in Southern India. The presence of hypokalemia with inappropriate kaliuresis (24 hr. urine K > 20mEq) was an important diagnostic clue. High resolution CT scans were found to be useful for localising the tumour. Preoperatively nifedipine and spironolactone were employed to correct hypertension and hypokalemia. The same drugs were also found to be excellent for long-term control of hypertension and hypokalemia in patients who had bilateral adrenal hyperplasia and aldosteronism.
M S Seshadri; A S Kanagasabapathy; A M Cherian; A Nair; S R Jesudason
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  41     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  1993 May 
Date Detail:
Created Date:  1994-03-04     Completed Date:  1994-03-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  266-8     Citation Subset:  IM    
Christion Medical College & Hospital, Vellore.
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MeSH Terms
Follow-Up Studies
Hyperaldosteronism / diagnosis*,  therapy
Hypokalemia / etiology
Middle Aged
Nifedipine / therapeutic use
Potassium / blood,  urine
Spironolactone / therapeutic use
Tomography, X-Ray Computed
Reg. No./Substance:
21829-25-4/Nifedipine; 52-01-7/Spironolactone; 7440-09-7/Potassium
Comment In:
J Assoc Physicians India. 1993 Nov;41(11):773   [PMID:  8054042 ]

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