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Primary hepatic leiomyosarcoma: Case report and literature review.
MedLine Citation:
PMID:  22046492     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Primary hepatic leiomyosarcoma are rare tumors with less than 30 cases reported in the English literature. Non specific presentations and often diagnosis delayed until they reach a large size, is the norm with therapy leading to an often dismal prognosis. A 67-year-old man presented complaining of abdominal pain and a palpable abdominal mass since Jan 2010. Abdominal ultrasonography and abdominal computed tomography revealed a large tumor in the left lobe of the liver. Surgical exploration was undertaken and an extended left hepatectomy with extension onto the dorsal part of segment 8 preserving the MHV with partial resection of segment 6 was undertaken. The weight of the resected specimen was 1300 g of the left lobectomy specimen and 8 g of the segment 6 partial resection specimen. The pathology report confirmed the diagnosis of leiomyosarcoma. On immunohistochemistry, the tumor cells were positive for smooth muscle actin stain. The patient is on regular follow up and is currently 9 mo post resection with no evidence of recurrence. We report the case of a resected primary hepatic leiomyosarcoma and emphasize the need for a global database for these rare tumors to promote a better and broader understanding of this less understood subject.
Authors:
Nairuthya Shivathirthan; Junji Kita; Yukihiro Iso; Hiroyuki Hachiya; Park Kyunghwa; Tokihiko Sawada; Keiichi Kubota
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of gastrointestinal oncology     Volume:  3     ISSN:  1948-5204     ISO Abbreviation:  World J Gastrointest Oncol     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-11-02     Completed Date:  2011-11-10     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101532470     Medline TA:  World J Gastrointest Oncol     Country:  China    
Other Details:
Languages:  eng     Pagination:  148-52     Citation Subset:  -    
Affiliation:
Nairuthya Shivathirthan, Junji Kita, Yukihiro Iso, Hiroyuki Hachiya, Park KyungHwa, Tokihiko Sawada, Keiichi Kubota, Second Department of Surgery, Dokkyo Medical University, 880 Kita Kobayashi, Mibu, Tochigi 321-0293, Japan.
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