Document Detail

Primary esophageal repair for Boerhaave's syndrome whatever the free interval between perforation and treatment.
MedLine Citation:
PMID:  15037257     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Boerhaave's syndrome is the most sinister cause of esophageal perforation responsible with mortality rate ranging from 20 to 30%. Combination of mediastinal contamination with microorganisms, gastric acid and digestives enzymes, long free interval between injury and initiation of treatment causes severe mediastinitis which is fatal in most untreated cases. The aim of this paper is to emphasize primary esophageal repair and resuscitation whatever the free interval from rupture and repair. METHODS: A retrospective review of patients treated for Boerhaave's syndrome in our department from January 1980 to February 2003 was performed. The principle of treatment was surgical treatment and avoidance of esophageal exclusion or esophagectomy whichever was possible. RESULTS: There were 25 patients (17 males and 8 females). All patients were operated on by primary esophageal repair, except for three who underwent immediate exclusion of the esophagus and one patient who deceased on arrival before being operated. Patients were classified according to free interval between perforation and treatment: group 1 (n=9; 36%) within the 24 h (range from 12 to 24 h) and group 2 (n=16; 64%) more than 24 h (range from 2 to 17 days). Altogether 6 patients deceased (24%). In hospital mortality rate for groups 1 and 2 was, respectively, 44% (four patients) and 13% (two patients), not significantly different. Mean hospital stay was 63 days. Two patients developed anastomotic leakage needing esophagectomy and retrosternal coloplasty in one or more steps. One patient developed pleural abscess treated by percutaneous drainage. Three patients presented temporary symptomatic esophageal stenosis, of whom one underwent dilation. CONCLUSIONS: Long free interval before treatment does not preclude primary esophageal repair in Boerhaave's syndrome. Esophageal exclusion may be more often than not avoided in most cases.
Jacques Jougon; Tarun Mc Bride; Frédéric Delcambre; Antonio Minniti; Jean-François Velly
Related Documents :
16731127 - Transthoracic heller myotomy for esophageal achalasia: analysis of long-term results.
10962677 - Presumed laryngo-pharyngeal reflux: investigate or treat?
20524757 - Dilated intercellular spaces in subtypes of gastroesophagic reflux disease.
15716997 - Ileocecal interpositional graft for gastric replacement after total gastrectomy.
24139867 - Vertebroplasty and kyphoplasty: national outcomes and trends in utilization from 2005 t...
24233407 - Entomopathogenic nematodes associated with essential oil of lippia sidoides for control...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery     Volume:  25     ISSN:  1010-7940     ISO Abbreviation:  Eur J Cardiothorac Surg     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-03-23     Completed Date:  2004-04-29     Revised Date:  2005-05-24    
Medline Journal Info:
Nlm Unique ID:  8804069     Medline TA:  Eur J Cardiothorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  475-9     Citation Subset:  IM    
Department of Thoracic Surgery, Haut-Lévêque Hospital, Bordeaux University Hospital, avenue de Magellan, 33604 Pessac, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Esophageal Perforation / complications,  radiography,  surgery*
Hospital Mortality
Mediastinitis / etiology
Middle Aged
Retrospective Studies
Risk Factors
Rupture, Spontaneous / complications,  radiography,  surgery
Survival Analysis
Time Factors
Treatment Outcome
Comment In:
Eur J Cardiothorac Surg. 2004 Oct;26(4):870; 870-1   [PMID:  15450600 ]
Eur J Cardiothorac Surg. 2005 Feb;27(2):356; author reply 356   [PMID:  15691702 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion.
Next Document:  Functional assessment of the cervical esophagus after gastric transposition and cervical esophagogas...