Document Detail

Primary duodenal adenocarcinoma associated with neurofibromatosis type 1.
MedLine Citation:
PMID:  11931536     Owner:  NLM     Status:  MEDLINE    
It is well known that patients with neurofibromatosis have an increased incidence of various neoplasms, most of these being tumors of neural-crest origin, including neurofibromas, leiomyomas, ganglioneuromas, paragangliomas, and carcinoids. However, the occurrence of small-bowel adenocarcinoma is rare. In this article, we report a patient with small-bowel adenocarcinoma, the seventh such reported case. We include a review of the literature and a brief discussion of the implications of this association. We suggest that the association between small-bowel adenocarcinomas and neurofibromatosis may not be fortuitous, and that small-bowel adenocarcinoma should be considered, in particular. in the differential diagnosis of gastrointestinal symptoms in patients with neurofibromatosis. Also, a definite histologic diagnosis must be made, with the employment of special staining techniques, because of the differing prognoses for various cell types.
Young-Eun Joo; Hyun-Soo Kim; Sung-kyu Choi; Jong-Sun Rew; Chang-Soo Park; Sei-Jong Kim
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of gastroenterology     Volume:  37     ISSN:  0944-1174     ISO Abbreviation:  J. Gastroenterol.     Publication Date:  2002  
Date Detail:
Created Date:  2002-04-04     Completed Date:  2002-10-23     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9430794     Medline TA:  J Gastroenterol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  215-9     Citation Subset:  IM    
Department of Internal Medicine, Chonnam National University Medical School, Kwangju, Korea.
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MeSH Terms
Adenocarcinoma / complications,  diagnosis*
Cholangiopancreatography, Endoscopic Retrograde / methods
Duodenal Neoplasms / complications,  diagnosis*
Middle Aged
Neurofibromatosis 1 / complications,  diagnosis*

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