| Primary cutaneous anaplastic large-cell lymphoma presenting with hemophagocytic syndrome: a case report and review of the literature. | |
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MedLine Citation:
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PMID: 19640585 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Primary cutaneous anaplastic large-cell lymphoma (C-ALCL) is a rare entity of lymphoma. We report a case of C-ALCL presenting with hemophagocytic syndrome and skin lesion with giant ulcer. Histopathological examination of the skin biopsy specimens showed non-epidermotropic infiltrates with cohesive sheets of large tumor cells. The tumor cells showed CD4-, CD8+, CD30+, CD56-, ALK-, TIA-1+, and granzyme B+. C-ALCL is generally a disorder that progresses slowly and has a good prognosis. Manifestation of a giant ulcer and hemophagocytic syndrome, such as in the present case, is rare. |
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Authors:
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Yoko Shimizu; Ken Tanae; Naoki Takahashi; Mika Kohri; Eiichi Arai; Masami Bessho; Nozomi Niitsu |
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Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2009-07-28 |
Journal Detail:
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Title: Leukemia research Volume: 34 ISSN: 1873-5835 ISO Abbreviation: Leuk. Res. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-01 Completed Date: 2010-03-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7706787 Medline TA: Leuk Res Country: England |
Other Details:
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Languages: eng Pagination: 263-6 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Hematology, Comprehensive Cancer Center, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama 350-1298, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Disease-Free Survival Humans Immunohistochemistry Lymphohistiocytosis, Hemophagocytic / etiology*, radiotherapy Lymphoma, Large-Cell, Anaplastic / complications*, radiotherapy Male Neoplasm Invasiveness Skin Neoplasms / etiology, pathology Skin Ulcer / etiology* |
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