Document Detail

Primary cutaneous CD30+ anaplastic large-cell lymphomas mimicking keratoacanthomas.
MedLine Citation:
PMID:  17953637     Owner:  NLM     Status:  MEDLINE    
Primary cutaneous anaplastic large cell lymphoma (ALCL) may be associated with keratoacanthoma (KA)-like epithelial hyperplasia and dense eosinophilic and neutrophilic infiltrates. Diagnosis in such cases is challenging both clinically and histologically, because the large atypical lymphoid cells may be obscured by the massive infiltrate of eosinophils and neutrophils, or confused with invasive squamous cell carcinoma or KA. We recently encountered two cases of CD30+ ALCL presenting with a KA-like tumour on the eyelid and nose, respectively. One showed features of KA histologically, with marked tissue eosinophilia and neutrophilia.
J M Martín; J M Ricart; C Monteagudo; J Alcácer; I Pinazo; L Tomás; N Rausell; E Jordá
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and experimental dermatology     Volume:  32     ISSN:  0307-6938     ISO Abbreviation:  Clin. Exp. Dermatol.     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-10-23     Completed Date:  2008-04-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7606847     Medline TA:  Clin Exp Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  668-71     Citation Subset:  IM    
Department of Dermatology, Hospital Clínico Universitario, Valencia, Spain.
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MeSH Terms
Diagnosis, Differential
Eyelid Neoplasms / diagnosis,  pathology
Facial Neoplasms / diagnosis*,  pathology
Keratoacanthoma / diagnosis*
Lymphoma, Primary Cutaneous Anaplastic Large Cell / diagnosis*,  pathology
Middle Aged
Nose Neoplasms / diagnosis,  pathology
Skin Neoplasms / diagnosis*,  pathology

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