Document Detail

Primary chronic angle-closure glaucoma in Chinese--a clinical exploration of its pathogenesis and natural course.
MedLine Citation:
PMID:  7744211     Owner:  NLM     Status:  MEDLINE    
Forty-three cases (86 eyes) of primary chronic angle-closure glaucoma were randomly selected. An additional 44 cases (77 eyes) of primary acute angle-closure glaucoma and 30 normal subjects (34 eyes) were also randomly enrolled as control groups for comparison in the clinical study. Ultrasonic biometric measurements of the anterior chamber depth, lens thickness and axial length of the eyeball were performed. Using an potic microgauge attached to the slit-lamp, the entrance of anterior chamber angle was also calculated. The clinical manifestations and the natural course, including the characteristic appearance of anterior chamber angle, the form of peripheral anterior synechia as well as the facility of outflow, were carefully investigated. There were significant differences in the biometric parameters of the anterior segment of eye among above three groups. The facts reveal that the anatomic features of eyeball, especially in the anterior segment differentiate from those of primary acute angle-closure glaucoma. Follow-up study for the early stage cases showed that topical administration of miotics and/or peripheral iridectomy can effectively prevent iris from forming peripheral anterior synechia and thus halt its development. The criteria of diagnosis and the principles of prevention and treatment at the early stage cases were presented. The pathogenesis was discussed. We emphasized that the progressive stage after intermittent attacks of primary acute angle-closure glaucoma should not be confused with primary chronic angle-closure glaucoma.
X Sun; X Ji; Y Zheng; B Guo
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Yan ke xue bao = Eye science / "Yan ke xue bao" bian ji bu     Volume:  10     ISSN:  1000-4432     ISO Abbreviation:  Yan Ke Xue Bao     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1995-06-15     Completed Date:  1995-06-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8605666     Medline TA:  Yan Ke Xue Bao     Country:  CHINA    
Other Details:
Languages:  eng     Pagination:  176-85     Citation Subset:  IM    
Department of Ophthalmology, Eye & ENT Hospital, Shanghai Medical University, China.
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MeSH Terms
Aged, 80 and over
Anterior Chamber / ultrasonography
Chronic Disease
Glaucoma, Angle-Closure* / diagnosis,  etiology,  therapy
Intraocular Pressure
Iris / surgery
Lens, Crystalline / ultrasonography
Middle Aged
Pilocarpine / therapeutic use
Random Allocation
Sex Factors
Reg. No./Substance:

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