Document Detail


Primary cardiac lymphoma: diagnostic tools and treatment challenges.
MedLine Citation:
PMID:  19921311     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Primary cardiac lymphoma (PCL) is a rare malignancy and the optimal treatment strategy remains uncertain. It appears to respond much better to systemic chemotherapy than to surgery and it should be considered in the differential diagnosis of all cardiac tumours before definitive management is undertaken. We report a case of this rare disorder treated successfully with a combination of rituximab and cyclophosphamide, adriamycin, vincristine and prednisolone. The patient developed recurrent unstable ventricular tachycardia (VT) post-chemotherapy secondary to extensive scarring at the tumour site. The tumour as well as the post-treatment scarring is well illustrated by cardiac magnetic resonance imaging highlighting its usefulness in this setting. An implantable cardioverter defibrillator (ICD) was placed. This is only the second case in the literature of PCL to have an ICD placed for recurrent VT. A brief literature review is included.
Authors:
R Bambury; F Gallagher; J D Dodd; D Fennelly
Publication Detail:
Type:  Journal Article     Date:  2009-11-17
Journal Detail:
Title:  Irish journal of medical science     Volume:  180     ISSN:  1863-4362     ISO Abbreviation:  Ir J Med Sci     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-01-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806864     Medline TA:  Ir J Med Sci     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  271-3     Citation Subset:  IM    
Affiliation:
Department of Medical Oncology, St Vincents University Hospital, Dublin 4, Ireland, richardbambury@hotmail.com.
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