Document Detail

Primary carcinosarcoma of the ear: case report and review of the literature.
MedLine Citation:
PMID:  20729953     Owner:  NLM     Status:  In-Data-Review    
Primary carcinosarcoma is a very rare neoplasm comprising two intermingling malignant components-epithelial and mesenchymal. The authors report a new case of primary cutaneous carcinosarcoma involving the helix of the ear. Immunohistochemical analysis revealed epithelial components of both basal cell and squamous cell carcinomas with a partially ossified sarcomatous-like component.Cutaneous carcinosarcoma (CS) is a neoplasm with dual epithelial and mesenchymal malignant components. It is most commonly seen in elderly males on sun-exposed areas of the body.(1-2) The histogenesis of CS is currently under debate. Immunohistochemistry plays an integral part in the diagnosis of this rare biphasic neoplasm. After a review of the literature, the authors were able to find only four other reported cases of CS involving the ear.(1,3) They present the fifth case of primary cutaneous CS, which involved the helix of the ear.
Susun Bellew; James Q Del Rosso; Narciss Mobini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of clinical and aesthetic dermatology     Volume:  2     ISSN:  1941-2789     ISO Abbreviation:  J Clin Aesthet Dermatol     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2010-08-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101518173     Medline TA:  J Clin Aesthet Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  33-5     Citation Subset:  -    
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