Document Detail


Primary carcinoma of the frontal sinus with extensive intracranial invasion: A case report and review of the literature.
MedLine Citation:
PMID:  24932258     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Primary carcinoma of the frontal sinus is quite rare, with an incidence of 0.3-1.0% of all paranasal sinus carcinomas. The early diagnosis is often difficult and the condition is often mistakenly considered to involve mucoceles, pyoceles or osteomyelitis. The present study reports the case of a 66-year-old male with squamous cell carcinoma originating in the frontal sinus. The presenting symptoms were a cutaneous nodule on the left side of the forehead and a gradually progressive headache. Magnetic resonance imaging (MRI) demonstrated erosion of the ethmoid sinus, frontal lobe and orbit. The radical resection under frontal craniotomy was performed followed by post-operative radiotherapy. Six months after the surgery, the MRI examinations did not find any recurrence, and the patient currently lives symptom-free. The present study illustrates that frontal sinus cancer should be diagnosed early with caution. Total surgical resection followed by radiotherapy and chemotherapy, used singly or in combination, may result in favorable outcomes. The current study discusses the diagnosis, treatment and prognosis of the present case and reviews the associated literature to emphasize the importance of an early identification of this rare disease.
Authors:
Heng-Zhu Zhang; Yu-Ping Li; Lei She; Xiao-Dong Wang; Zheng-Cun Yan; Nan Zhang; En-Xi Xu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-4-03
Journal Detail:
Title:  Oncology letters     Volume:  7     ISSN:  1792-1074     ISO Abbreviation:  Oncol Lett     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101531236     Medline TA:  Oncol Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1915-1918     Citation Subset:  -    
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