Document Detail


Primary carcinoma of the fallopian tube.
MedLine Citation:
PMID:  3013008     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
From 1964 through 1983, 47 patients with a mean age of 63 years underwent primary treatment of fallopian tube carcinoma. Vaginal bleeding, abdominopelvic pain or pressure, and a palpable pelvic mass (or masses) were frequent retrospective clinical associations. Survival analysis demonstrated a rapid initial rate of patient attrition with stabilization after 3 years, resulting in an overall 5-year survival rate of 41%. While independent of age, histologic grade, or original tumor size, patient longevity was significantly decreased (p less than 0.01) by the presence of disease beyond the pelvis, neoplastic cells in the peritoneal washings, and size of residual disease. Therapy consisted of primary surgical resection, usually followed by adjunctive radiotherapy or chemotherapy. Initial sites of relapse were predominantly (88%) within the intraperitoneal cavity. The study supports definitive surgical staging and tumor reduction, as well as more selective adjuvant therapy based on surgical stage and residual tumor size and location.
Authors:
K C Podratz; E S Podczaski; T A Gaffey; P C O'Brien; M F Schray; G D Malkasian
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  154     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1986 Jun 
Date Detail:
Created Date:  1986-07-10     Completed Date:  1986-07-10     Revised Date:  2006-04-24    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1319-26     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / mortality,  secondary,  surgery*
Aged
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Brachytherapy
Combined Modality Therapy
Fallopian Tube Neoplasms / mortality,  pathology,  surgery*
Female
Follow-Up Studies
Humans
Middle Aged
Neoplasm Invasiveness
Neoplasm Recurrence, Local
Neoplasm Staging
Neoplasms, Germ Cell and Embryonal / mortality,  secondary,  surgery*
Palpation
Peritoneal Neoplasms / secondary
Radiotherapy Dosage
Reoperation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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