| Primary blood TSH/back up TSH measurements: an improved approach for neonatal thyroid screening. | |
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MedLine Citation:
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PMID: 21254245 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objective: Neonatal hypothyroidism is one of the most common endocrine disorders related to mental impairment and growth retardation in newborns. In many countries, the neonatal thyroid screening programs are performed for rapid diagnosis and treatment of hypothyroidism. The major aim of this investigation was to improve the thyroid screening program using primary blood TSH/back up TSH measurements as some patients are missed due to technical and human errors. Methods: A total of 9,118neonates were evaluated on the protocol. On top of that, the quality control procedures were applied to improve the sampling technique and the laboratory results. Results: Three missed neonates by current programs using the cutoff point more than 20 mU/l for blood TSH were found by our approach. Conclusion: Results showed that the programs based on the primary blood TSH/back up TSH measurements improve the thyroid screening results. J. Clin. Lab. Anal. 25:61-63, 2011. © 2011 Wiley-Liss, Inc. |
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Authors:
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Mohammad Najafi; Mostafa Mazlom Farsi; Masoumeh Sabahi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical laboratory analysis Volume: 25 ISSN: 1098-2825 ISO Abbreviation: J. Clin. Lab. Anal. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-01-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8801384 Medline TA: J Clin Lab Anal Country: United States |
Other Details:
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Languages: eng Pagination: 61-3 Citation Subset: IM |
Copyright Information:
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© 2011 Wiley-Liss, Inc. |
Affiliation:
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Biochemistry Department, Cellular and Molecular Research Center, Tehran University of Medical Sciences, Tehran, Iran. nbsmmsbn@iums.ac.ir. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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