| Primary billiary cirrhosis (antimitochondrial antibody negative) leading to secondary amyloidosis. | |
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MedLine Citation:
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PMID: 22538043 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A 49 years old lady presented with low-grade fever (99-100°F) for 2 years. During this time she was extensively workedup for pyrexia of unknown origin but no diagnosis could be established. Her Initial blood work-up was all negative except high alkaline phosphatase and gamma GT (374 IU and 195 IU respectively). She later presented to our tertiary care centre with facial swelling, flushing and bilateral pedal swelling for 3 months. Along with generalized body swelling she had frothy urine. She was diagnosed as nephrotic syndrome on the basis of nephrotic range proteinuria. Her Renal biopsy done for workup of nephrotic was positive for AA amyloid. Also, her gastrointestinal biopsy was suggestive of amyloidosis. As a workup for secondary amyloidosis, her liver biopsy was done which revealed features of primary billiary cirrhosis (PBC). |
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Authors:
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Om Parkash; Aysha Almas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP Volume: 22 ISSN: 1681-7168 ISO Abbreviation: J Coll Physicians Surg Pak Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-04-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9606447 Medline TA: J Coll Physicians Surg Pak Country: Pakistan |
Other Details:
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Languages: eng Pagination: 330-2 Citation Subset: IM |
Affiliation:
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Department of Medicine, The Aga Khan University Hospital, Karachi. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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