| Primary biliary cirrhosis complicated by transverse myelitis in a patient without Sjögren's syndrome. | |
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MedLine Citation:
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PMID: 15793339 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Transverse myelitis is an acute inflammatory process, affecting one or more segments of the spinal cord. Its association with primary biliary cirrhosis has been documented in only four cases--all along with Sjögren's syndrome. Herein, we report for the first time, a patient who developed recurrent acute transverse myelitis in association with primary biliary cirrhosis without any clinical or histological indication of Sjögren's syndrome. A 42-year-old woman with primary biliary cirrhosis developed acute onset quadriparesis and urinary retention. Diagnostic evaluation excluded the presence of Sjögren's syndrome, other autoimmune syndromes, infections and multiple sclerosis. Magnetic resonance imaging of the spinal cord disclosed signal intensity abnormalities from C1 to T2 after gadolinium enhancement. As diagnosis of acute transverse myelitis was prominent, the patient was treated with intravenous methylprednisolone. The patient had a fair outcome despite an early recurrence of the symptoms after treatment withdrawal. |
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Authors:
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V Papadopoulos; A Micheli; D Nikiforidis; K Mimidis |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of postgraduate medicine Volume: 51 ISSN: 0022-3859 ISO Abbreviation: J Postgrad Med Publication Date: 2005 Jan-Mar |
Date Detail:
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Created Date: 2005-03-28 Completed Date: 2006-04-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985196R Medline TA: J Postgrad Med Country: India |
Other Details:
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Languages: eng Pagination: 43-4 Citation Subset: IM |
Affiliation:
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First Department of Internal Medicine, Democritus University of Thrace, Greece. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Inflammatory Agents / therapeutic use Female Humans Liver Cirrhosis, Biliary / complications* Methylprednisolone / therapeutic use Myelitis, Transverse / complications*, diagnosis, drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 83-43-2/Methylprednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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