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Primary antiphospholipid antibody syndrome presenting with encephalopathy, psychosis and seizures.
MedLine Citation:
PMID:  21768180     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by recurrent thrombotic events, miscarriages and thrombocytopenia with persistently positive antiphospholipid antibodies.(1,2) APS may be isolated (primary APS) or associated to a connective tissue disease, most often systemic lupus erythematosus (SLE).(1,2) APS usually affects young patients before the fifth decade(3) with stroke being the commonest neurological manifestation.(4) Various other neurological manifestations are being recognized in patients with APS including migraine, epilepsy, multi-infarct dementia and chorea.(2) The pathological process underlying the neurological manifestations remains obscure.(1,2) Herein we report a case of primary APSpresenting with a group of unusual neurological manifestations in a 68-year-old woman.
Authors:
R Taipa; E Santos
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-18
Journal Detail:
Title:  Lupus     Volume:  -     ISSN:  1477-0962     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204265     Medline TA:  Lupus     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Neurology, Hospital de Santo António, Porto, Portugal.
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