Document Detail

Primary angiitis of the central nervous system: report of two cases and review of the literature.
MedLine Citation:
PMID:  7708155     Owner:  NLM     Status:  MEDLINE    
Two cases of primary angiitis of the central nervous system with subarachnoid hemorrhage are reported. One patient was admitted with very thin and localized sulcal subarachnoid hemorrhage, followed by the development of multiple parenchymal edema. Although the first angiography showed only a mild narrowing of an artery, the second angiography demonstrated multiple segmental narrowings of arteries. An open biopsy failed to show histological changes. The second patient suffered from sylvian subarachnoid hemorrhage along with multiple intracerebral hemorrhages, with angiography that was diagnostic for angiitis. In both cases, predonine was initiated and further angiography clearly demonstrated a resolution of the angiitis. The usefulness of serial angiography for diagnosis in comparison with surgical biopsy and for monitoring the treatment of this disease is discussed. The occurrence of subarachnoid hemorrhage in this disease is also reviewed.
T Ozawa; O Sasaki; T Sorimachi; R Tanaka
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Neurosurgery     Volume:  36     ISSN:  0148-396X     ISO Abbreviation:  Neurosurgery     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1995-05-09     Completed Date:  1995-05-09     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7802914     Medline TA:  Neurosurgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  173-9; discussion 179     Citation Subset:  IM    
Department of Neurosurgery, Niigata University, Japan.
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MeSH Terms
Cerebral Angiography*
Cerebral Arteries / pathology
Cerebrovascular Disorders / diagnosis*,  drug therapy
Cyclophosphamide / therapeutic use
Middle Aged
Neurologic Examination / drug effects
Parietal Lobe / blood supply
Prednisolone / therapeutic use
Subarachnoid Hemorrhage / diagnosis,  drug therapy
Vasculitis / diagnosis*,  drug therapy
Reg. No./Substance:
50-18-0/Cyclophosphamide; 50-24-8/Prednisolone

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