| Primary angiitis of the central nervous system with diffuse cerebral mass effect and giant cells. | |
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MedLine Citation:
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PMID: 20303761 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Primary angiitis of the central nervous system (PACNS), also called primary CNS vasculitis, is an idiopathic inflammatory condition affecting only intracranial and spinal cord vessels, particularly medium-sized and smaller arteries and arterioles. Angiography and histopathology typically do not reveal evidence of systemic vasculitis.(1,2) Histopathology usually reveals granulomatous inflammation affecting arterioles and small arteries of the parenchyma and/or leptomeninges, similar to that seen in Takayasu's or giant cell arteritis.(1-3) We report a patient with biopsy-proven PACNS with giant cells and cerebral mass effect on MRI. Magnetic resonance angiography and cerebral angiography appeared normal and there was no evidence of extracranial vasculitis. |
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Authors:
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J A Kinsella; W O'Brien; G M Mullins; J Brewer; S Whyte |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-03-19 |
Journal Detail:
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Title: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia Volume: 17 ISSN: 1532-2653 ISO Abbreviation: J Clin Neurosci Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-03-29 Completed Date: 2010-06-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9433352 Medline TA: J Clin Neurosci Country: Scotland |
Other Details:
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Languages: eng Pagination: 674-6 Citation Subset: IM |
Affiliation:
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Department of Neurology, The Adelaide and Meath Hospital, Dublin, Incorporating the National Children's Hospital, Trinity College Dublin, Tallaght, Dublin 24, Ireland. justinkinsella@gmail.com <justinkinsella@gmail.com> |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged, 80 and over Anti-Inflammatory Agents / therapeutic use Brain / pathology*, radiography Cerebral Angiography Cerebrovascular Circulation Female Giant Cells / pathology* Humans Magnetic Resonance Imaging Prednisolone / therapeutic use Treatment Outcome Vasculitis, Central Nervous System / drug therapy, pathology*, radiography |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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