Document Detail

Primary adenosquamous carcinoma of the liver: case report.
MedLine Citation:
PMID:  12658415     Owner:  NLM     Status:  MEDLINE    
We describe a case of adenosquamous carcinoma of the liver, including treatment for the recurrence. A 67-year-old man with prolonged high fever was diagnosed with a mass lesion in the left lobe of the liver seen by imaging studies. That mass lesion was histologically diagnosed as cholangiocarcinoma by needle biopsy. Left hepatic lobectomy was performed, and a tumor was found that measured 8.0 x 7.0 x 6.0 cm. It was a yellowish white solid mass without macroscopic invasion of the intrahepatic bile duct. Histological examination of the resected specimen revealed both adenocarcinoma and squamous cell carcinoma. The postoperative course was uneventful, but abdominal computed tomography 3 months after operation revealed seven masses in the remnant liver. We diagnosed recurrence of the tumor, and intrahepatic arterial infusion of cisplatin and 5-fluorouracil was begun. A partial remission resulted. Progression-free survival after chemotherapy lasted 2 months. However, the tumor markers and remnant tumor size increased gradually 9 months after the operation, and he died 14 months after surgery. We also review 41 cases of adenosquamous carcinoma of the liver reported in the Japanese and English language literature, including the present case.
Eiji Suzuki; Ryuji Hirai; Tetsuya Ota; Nobuyoshi Shimizu
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of hepato-biliary-pancreatic surgery     Volume:  9     ISSN:  0944-1166     ISO Abbreviation:  J Hepatobiliary Pancreat Surg     Publication Date:  2002  
Date Detail:
Created Date:  2003-03-26     Completed Date:  2003-10-08     Revised Date:  2006-04-24    
Medline Journal Info:
Nlm Unique ID:  9431940     Medline TA:  J Hepatobiliary Pancreat Surg     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  769-73     Citation Subset:  IM    
Second Department of Surgery, Okayama University Medical School, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Carcinoma, Adenosquamous / pathology,  surgery*
Cisplatin / administration & dosage
Fatal Outcome
Fluorouracil / administration & dosage
Infusions, Intra-Arterial
Liver Neoplasms / pathology,  surgery*
Neoplasm Recurrence, Local / drug therapy
Reg. No./Substance:
15663-27-1/Cisplatin; 51-21-8/Fluorouracil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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