| Primary adenocarcinoma in an enterocutaneous fistula associated with Crohn's disease. | |
| | |
MedLine Citation:
|
PMID: 9659564 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Increasing numbers of intestinal adenocarcinomas in patients with Crohn's disease have been reported, but the strength of this association still needs to be elucidated. Adenocarcinoma has also been documented in different types of fistulous tracts associated with Crohn's disease. The first case of well-differentiated mucinous adenocarcinoma involving only enterocutaneous fistulae is reported in a patient with long-standing Crohn's disease complicated by persistent abdominal wall fistulous tracts. The malignant lesion arose from neoplastic transformation of columnar epithelium lining portions of the fistulae occurring as a result of either re-epithelialization of these inflammatory tracts or mural implantation of mucosal tissue secondary to prior ulceration. The patient has remained disease-free eight years after surgical resection of the tumour. Even though intestinal carcinoma is not as strongly associated with Crohn's disease as with ulcerative colitis, intestinal carcinoma should be considered in the setting of long-standing disease, previous intestinal exclusion surgeries and complications such as enterocutaneous or other types of fistulous tracts. The prognosis of such patients may be excellent with early diagnosis and treatment. |
| | |
Authors:
|
L T Ying; D J Hurlbut; W T Depew; A H Boag; K Taguchi |
Related Documents
:
|
16227104 - Distal lower extremity paresthesia and foot drop developing during adalimumab therapy. 19916954 - Anti-tnf and fistulizing perianal crohn's disease: use in clinical practice. 20061984 - Neutrophil gelatinase-associated lipocalin levels in patients with crohn disease underg... 17602974 - Perianal crohn's disease. 22870494 - Juvenile dermatomyositis: new insights and new treatment strategies. 467574 - Isolation of di-n-2-propylpentyl phthalate from human urine. |
Publication Detail:
|
Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Canadian journal of gastroenterology = Journal canadien de gastroenterologie Volume: 12 ISSN: 0835-7900 ISO Abbreviation: Can. J. Gastroenterol. Publication Date: 1998 May-Jun |
Date Detail:
|
Created Date: 1998-09-15 Completed Date: 1998-09-15 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8807867 Medline TA: Can J Gastroenterol Country: CANADA |
Other Details:
|
Languages: eng Pagination: 265-9 Citation Subset: IM |
Affiliation:
|
Department of Medicine, Queen's University, Kingston, Ontario. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenocarcinoma, Mucinous
/
complications*,
diagnosis,
surgery Crohn Disease / complications*, surgery Cutaneous Fistula / complications*, diagnosis, surgery Follow-Up Studies Humans Ileum / surgery Intestinal Fistula / complications*, diagnosis, surgery Intestinal Neoplasms / complications*, diagnosis, surgery Male Middle Aged Postoperative Complications |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effect of hyperbaric oxygen on lipid peroxidation in free skin grafts in rats.
Next Document: Castleman's disease and neutropenic enterocolitis presenting as Crohn's disease.