| Primary T-cell lymphoma of the thyroid associated with Hashimoto's thyroiditis, histologically mimicking MALT-lymphoma. | |
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MedLine Citation:
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PMID: 20191052 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Most of thyroid lymphomas are B-lineage, and T-cell lymphomas are rare. Here, we report a case of primary thyroid T-cell lymphoma associated with Hashimoto's thyroiditis. A 48-yr-old woman presented with incidentally found neck mass. Histologically, the resected right lobe of the thyroid was replaced by monomorphic small atypical lymphoid cells with lymphoepithelial lesion-like change, most of which were immunoreactive for CD3, CD8, betaF-1, and TIA-1. Peripheral T-cell lymphoma, unspecified, was finally diagnosed after molecular study for TCR-gamma gene rearrangement. This is the second case of cytotoxic T-cell lymphoma reported in the thyroid gland so far. Unique association between thyroid follicles and neoplastic lymphocytes may be characteristic feature of this type of T-cell lymphoma. |
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Authors:
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Na Rae Kim; Young-Hyeh Ko; Young-Don Lee |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-02-19 |
Journal Detail:
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Title: Journal of Korean medical science Volume: 25 ISSN: 1598-6357 ISO Abbreviation: J. Korean Med. Sci. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-01 Completed Date: 2010-05-18 Revised Date: 2010-09-30 |
Medline Journal Info:
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Nlm Unique ID: 8703518 Medline TA: J Korean Med Sci Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 481-4 Citation Subset: IM |
Affiliation:
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Department of Pathology, Gachon University of Medicine and Science, Gil Medical Center, Incheon, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Hashimoto Disease / pathology* Humans Lymphoma, B-Cell, Marginal Zone / pathology* Lymphoma, T-Cell / pathology* Middle Aged T-Lymphocyte Subsets / immunology, pathology T-Lymphocytes, Cytotoxic / immunology, pathology Thyroid Gland / pathology* |
| Comments/Corrections | |
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