Document Detail

Primary synovial sarcoma of the lung with intra-cardiac extension.
MedLine Citation:
PMID:  20714127     Owner:  NLM     Status:  In-Data-Review    
Synovial sarcomas are a distinct clinical entity occurring most often in the lower extremities. They account for 10-14% of all soft tissue sarcomas. Pulmonary synovial sarcomas are quite rare and account for less than 0.5% of all intra-thoracic neoplasms. We present the first reported case of primary pulmonary synovial sarcoma with intra cardiac extension in a 53-year-old male who presented with chronic cough. Imaging revealed a large right upper lobe mass extending through the superior pulmonary veins into the left atrium. The patient underwent a right total pneumonectomy with extraction of the left atrial mass and left atrial reconstruction. Pathology and immunohistochemistry was diagnostic of primary pulmonary synovial sarcoma positive for SYT-SSX1 gene fusion transcription.
Veena S Devarakonda; Larissa Lembert; John W Entwistle; Jeffrey B Hoag
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Publication Detail:
Type:  Journal Article     Date:  2010-08-14
Journal Detail:
Title:  Respiration; international review of thoracic diseases     Volume:  81     ISSN:  1423-0356     ISO Abbreviation:  Respiration     Publication Date:  2011  
Date Detail:
Created Date:  2011-03-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0137356     Medline TA:  Respiration     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  249-52     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 S. Karger AG, Basel.
Division of Pulmonary, Critical Care and Sleep Medicine, Drexel University College of Medicine, Philadelphia, Pa., USA.
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