| Primary metastatic leiomyosarcoma of the fallopian tube: a rare case report. | |
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MedLine Citation:
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PMID: 20164662 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Leiomyosarcoma of the fallopian tube is an extremely unusual gynecologic neoplasm. Since 1886, only 19 of about 35 sarcomas of the fallopian tube have been identified as leiomyosarcomas. As such, clinical diagnosis and therapy management are difficult. CASE REPORT: We report on the case of a 59-year-old woman with leiomyosarcoma of the fallopian tube and liver metastases at the time of diagnosis. After initial tumor debulking, she received palliative chemotherapy with gemcitabine 900 mg/m(2) (d1+8) and docetaxel 100 mg/m(2) (d8) (q21). For additional bone metastases, she started local radiation plus bisphosphonates (q28). After 2 cycles of chemotherapy, the disease progressed, and the patient died within 8 months of diagnosis. A review of the literature is given. CONCLUSIONS: Primary metastatic leiomyosarcoma of the fallopian tube is a progressive disease with limited therapy options. For better prognostic evaluation and disease management in such rare cases, it is important to report and compare more cases regarding course of disease and outcome. |
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Authors:
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Volker R Jacobs; Iris Zemzoum; Marcus Kremer; Nina Gottschalk; Anne K Baumg?rtner; Janna Krol; Marion Kiechle |
Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2010-01-22 |
Journal Detail:
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Title: Onkologie Volume: 33 ISSN: 1423-0240 ISO Abbreviation: Onkologie Publication Date: 2010 |
Date Detail:
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Created Date: 2010-02-18 Completed Date: 2010-06-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7808556 Medline TA: Onkologie Country: Switzerland |
Other Details:
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Languages: eng Pagination: 49-52 Citation Subset: IM |
Copyright Information:
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(c) 2010 S. Karger AG, Basel. |
Affiliation:
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Department of Obstetrics and Gynecology, Technical University Munich, Germany. volkerjacobs@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Combined Modality Therapy Diagnostic Imaging Disease Progression Fallopian Tube Neoplasms / diagnosis*, pathology, therapy Fallopian Tubes / pathology Fatal Outcome Female Humans Leiomyosarcoma / diagnosis, pathology, secondary*, therapy Liver / pathology Liver Neoplasms / diagnosis, pathology, secondary*, therapy Middle Aged Neoplasm Invasiveness / pathology Neoplasm Staging Palliative Care Peritoneal Neoplasms / diagnosis, pathology, secondary*, therapy Prognosis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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