| Primary lymphoedema and lymphatic malformation: are they the two sides of the same coin? | |
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MedLine Citation:
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PMID: 20176496 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To clear the confusion regarding the relationship between the 'primary lymphoedema' and (truncular) lymphatic malformation (LM); the latter is one of congenital vascular malformations. MATERIALS & METHODS: A literature review was carried out on the primary lymphoedema either existing as an independent LM lesion or as a component of the Klippel-Trenaunay syndrome. RESULTS: The review was able to provide a contemporary guide/conclusion on the definition and classification, clinical evaluation and clinical management regarding conservative (physical) therapy, reconstructive surgical therapy and ablative/excisional surgical therapy, for the primary lymphoedema as an LM. CONCLUSIONS: Primary lymphoedema can be considered as 'congenital' since its majority represents a clinical manifestation of the truncular type of LM arising during the later stages of lymphangiogenesis. Such embryological staging information of the LM is critical for proper management of the primary lymphoedema when it exists with other congenital vascular malformations (Klippel-Trenaunay syndrome). 2. Basic non-invasive to minimally invasive tests will provide an adequate diagnosis and lead to the correct multidisciplinary, specifically targeted and sequenced treatment strategy. 3. The mainstay of current management of the primary lymphoedema/truncular LM is complex decongestive therapy; and the reconstructive as well as ablative surgical therapy remain adjunctive therapies at best. |
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Authors:
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B B Lee; J L Villavicencio |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-02-21 |
Journal Detail:
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Title: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery Volume: 39 ISSN: 1532-2165 ISO Abbreviation: Eur J Vasc Endovasc Surg Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-03 Completed Date: 2010-05-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9512728 Medline TA: Eur J Vasc Endovasc Surg Country: England |
Other Details:
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Languages: eng Pagination: 646-53 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Division of Vascular Surgery, Georgetown University School of Medicine, Washington, DC 20007, USA. bblee38@comcast.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Combined Modality Therapy Humans Klippel-Trenaunay-Weber Syndrome / classification*, diagnosis, therapy Lymphatic Abnormalities / classification*, diagnosis, therapy Lymphedema / classification*, congenital, diagnosis, therapy Predictive Value of Tests Terminology as Topic* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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