Document Detail


Primary Leydig cell tumour of epididymis: a rare case report with review of literature.
MedLine Citation:
PMID:  23194277     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Leydig cell tumour (LCT) is an uncommon tumour that typically occurs in the testis. Primary epididymal LCT is extremely rare. To the best of our knowledge, only two cases have been reported in the world literature. Herein, we report a case of primary epididymal LCT in a 41-year-old Chinese male. The patient presented with right epididymal swelling for 3 months without endocrine manifestations, including gynaecomastia and decreased libido. Scrotal ultrasound demonstrated a mass about 1.5 cm in diameter entirely in the cephalic region of right epididymis. No abnormality was found in his bilateral testes. The patient underwent total mass resection without post-operative therapy. Histological examination revealed that the well-circumscribed tumour was separated by conspicuous hyalinised fibrous stroma; the tumour cells were large and polygonal with round nuclei and abundant eosinophilic cytoplasm. Immunophenotypically, the tumour cells expressed four markers of sex cord differentiation (calretinin, melanA, CD99 and inhibin). There was no recurrence at 2-year follow-up. Our observation once again confirms that LCT could primarily occur in the epididymis, and we suppose that it probably originates from the ectopic Leydig cells. As little is known about the pathogenesis and prognosis for such a rare disease, accumulation of more pathological and clinical data can help to better interpret this tumour.
Authors:
Y Huang; J Song; M Xu; Q Zan
Related Documents :
24995227 - Coexistence of glomangioma and yolk sac tumour in a child: a case report.
17479877 - Pure red cell aplasia due to treatment with epoietin beta: first case report of prca fr...
23739907 - Merkel cell carcinoma in elderly: case report and review of the literature.
24729347 - Does "cerebellar liponeurocytoma" always reflect an expected site? an unusual case with...
23971437 - How do reviewers affect the final outcome? comparison of the quality of peer review and...
17898677 - Partner notification for gonococcal and chlamydial infections in men who have sex with ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-29
Journal Detail:
Title:  Andrologia     Volume:  -     ISSN:  1439-0272     ISO Abbreviation:  Andrologia     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0423506     Medline TA:  Andrologia     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Blackwell Verlag GmbH.
Affiliation:
Department of Pathology, Shenzhen Second People's Hospital, Shenzhen, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Online Coupling of Capillary Electrophoresis with Direct Analysis in Real Time Mass Spectrometry.
Next Document:  A teenager with uncontrolled hypertension: a case report.