| Primary hyperparathyroidism in pregnancy: a diagnostic and therapeutic challenge. | |
| | |
MedLine Citation:
|
PMID: 20469964 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
The risk of severe complications arising from primary hyperparathyroidism (pHPT) is increased during pregnancy. Gestational pHPT often goes undiagnosed, and by the time it is diagnosed, a majority of women have endured one or more failed pregnancies. During pregnancy, active transport of calcium ions from the mother to the fetus leads to suppression of the fetal parathyroids. When the prenatal pool of calcium is depleted, the newborn may develop neonatal hypocalcemic tetany. The mother, in turn, may suffer from worsening hypercalcemia and a hypercalcemic crisis after delivery. Awareness and confirmation of the diagnosis may be crucial for the outcome. The only definitive treatment of pHPT is parathyroidectomy, which should be recommended in most cases. Our two cases illustrate both the importance of and the difficulty in detecting pHPT during pregnancy, as well as some of the serious complications that may occur during pregnancy and after delivery. |
| | |
Authors:
|
I-L Nilsson; N Adner; E Reihnér; C Palme-Kilander; G Edstrom; M Degerblad |
Related Documents
:
|
12957554 - Biomechanical and anatomical consequences of carpal tunnel release. 20978994 - Global hemostasis in pregnancy: are we using thromboelastography to its full potential? 2566534 - Retained pregnancy complicating donor ovum transfer. 3651944 - Maternal and neonatal outcome in pregnancies with no risk factors. 1563654 - The accuracy of the assessment of normal fetal intestinal echogenicity--electro-optical... 8173014 - Serum erythropoietin in small for gestational age fetuses. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of women's health (2002) Volume: 19 ISSN: 1931-843X ISO Abbreviation: J Womens Health (Larchmt) Publication Date: 2010 Jun |
Date Detail:
|
Created Date: 2010-06-15 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101159262 Medline TA: J Womens Health (Larchmt) Country: United States |
Other Details:
|
Languages: eng Pagination: 1117-21 Citation Subset: IM |
Affiliation:
|
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. inga-lena.nilsson@ki.se |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Women's health outcomes after traumatic brain injury.
Next Document: A High-Content RNAi-Screening Assay to Identify Modulators of Cholesterol Accumulation in Niemann-Pi...