| Primary Follicular Dendritic Cell Sarcoma of the Thyroid Gland Coexisting With Hashimoto's Thyroiditis. | |
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MedLine Citation:
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PMID: 19448067 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Follicular dendritic cell (FDC) sarcoma, especially of extranodal origin, is an extremely rare malignancy of FDC origin, with only 1 case previously documented in the thyroid. The authors report the case of a 58-year-old female who presented with a painless mass in her neck. The neoplastic cells expressed monocyte/macrophage-specific marker CD68 (KP-1) and lysozymes and the dendritic cell-associated antigens CD35 and Fascin but was negative for CD1a, CD21, and CD23, most consistent with a diagnosis of FDC sarcoma. BIOMED-2 multiplex polymerase chain reaction analysis showed B-cell clonality in both tumor and its adjacent coexisting Hashimoto's thyroiditis. To the authors' knowledge, this is the first report of a rare entity of FDC sarcoma primarily involving the thyroid gland coexisting with Hashimoto's thyroiditis. |
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Authors:
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Lu Yu; Shou Jing Yang |
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Publication Detail:
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Type: Journal Article Date: 2009-05-15 |
Journal Detail:
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Title: International journal of surgical pathology Volume: 19 ISSN: 1940-2465 ISO Abbreviation: Int. J. Surg. Pathol. Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-08-31 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9314927 Medline TA: Int J Surg Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 502-5 Citation Subset: IM |
Affiliation:
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1Pathology, Xi Jing Hospital, 4th Military Medical University, Xi'an, Shaanxi 710032, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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