| Primary Ewing's sarcoma of vulva: A case report and a review of the literature. | |
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MedLine Citation:
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PMID: 23106919 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Ewing sarcomas/peripheral primitive neuroectodermal tumors (ES/pPNET) are extremely rare in the vulva. A review of the literature reveals only 14 previously reported possible cases. Here we reported a case of primary extraskeletal Ewing's sarcoma (EES) of the vulva in a 37-year-old woman. Characteristic histologic features of ES/pPNET were present in this case, including a monomorphic population of small round blue cells with cytoplasmic glycogen confirmed by periodic acid-Schiff, membrane staining with CD99 and nuclear staining with FLI-1. After surgery, the patient was found to have pulmonary metastasis and then received six cycles of polychemotherapy. She is still alive with stable disease after 1 year of follow up. Our findings underline the crucial role of immunohistochemical techniques in the differential diagnosis of small round cell tumors in these unusual locations. We also give a summary about the clinical and pathological features of the primary ES/pPNET in the vulva reported previously in the literature. |
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Authors:
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Shao-Min Che; Pei-Long Cao; Hong-Wei Chen; Zi Liu; Du Meng |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-29 |
Journal Detail:
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Title: The journal of obstetrics and gynaecology research Volume: - ISSN: 1447-0756 ISO Abbreviation: J. Obstet. Gynaecol. Res. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9612761 Medline TA: J Obstet Gynaecol Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 The Authors. Journal of Obstetrics and Gynaecology Research © 2012 Japan Society of Obstetrics and Gynecology. |
Affiliation:
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Department of Radiation Oncology, Xi'an Jiaotong University School of Medicine, Xi'an, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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