Document Detail

Primary CNS lymphoma associated with streptococcal abscess: an autopsy case.
MedLine Citation:
PMID:  10746967     Owner:  NLM     Status:  MEDLINE    
This report describes a case of streptococcal abscess in the nodules of a primary central nervous system (CNS) lymphoma. Magnetic resonance imaging (MRI) of the brain revealed multiple lesions with ringlike enhancement over the bilateral frontal, right temporal, and left parietal lobes. On admission, acute brain edema occurred following angiography, which resulted in respiratory arrest. Autopsy findings showed that the ringlike enhanced lesions on MRI were streptococcal abscesses localized in the lymphoma nodules. The lymphoma was classified as non-Hodgkin, diffuse large cells of B-cell lineage. No other lymphoma mass was found extracranially. An immunohistochemical study showed that the lymphoma cells were positive for leukocyte common antigen, Epstein-Barr virus, bax. and bcl-XL, and negative for L-26 and bcl-2. This case demonstrated that an opportunistic streptococcal abscess developed in primary CNS lymphoma in a patient without acquired immunodeficiency syndrome (AIDS), though a few similar cases have been reported in patients with AIDS.
M Kano; M Watanabe; M Maeda
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Brain tumor pathology     Volume:  16     ISSN:  1433-7398     ISO Abbreviation:  Brain Tumor Pathol     Publication Date:  1999  
Date Detail:
Created Date:  2000-06-19     Completed Date:  2000-06-19     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9716507     Medline TA:  Brain Tumor Pathol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  92-7     Citation Subset:  IM; X    
Department of Neurosurgery, Chuno Hospital, Seki City, Gifu, Japan.
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MeSH Terms
Brain Abscess / complications*,  pathology
Brain Edema / etiology
Brain Neoplasms / complications*,  pathology
Cerebral Angiography / adverse effects
Fatal Outcome
Fever / etiology
Headache / etiology
Lymphoma, B-Cell / complications*,  pathology
Lymphoma, Non-Hodgkin / complications*,  pathology
Magnetic Resonance Imaging
Middle Aged
Paresis / etiology
Streptococcal Infections / complications*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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