Document Detail


Priapism complicating chronic granulocytic leukemia.
MedLine Citation:
PMID:  6940443     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Since 1952 we have seen nine patients with priapism leading to a diagnosis of chronic granulocytic leukemia (CGL) and a tenth patient who gave a history of priapism when CGL was diagnosed as a result of other symptoms. Seven patients had had one or more transient episodes of prolonged erection before the diagnosis of CGL was established. All ten had high blood leukocyte counts (mean 380 X 10(9)/liter, range 186-782) in comparison with other newly diagnosed patients. We estimate the incidence of this complication at 1%-2% of all male patients presenting with CGL. Treatment of patients in this series varied greatly. Five patients were treated mainly by local measures with r without cytotoxic drugs at conventional dosage, three were treated by sapheno-cavernous bypass operations and leukapheresis followed by cytotoxic drugs at high dosage, and two were treated initially by leukapheresis alone. In general, the prompt initiation of measures designed to reduce the leukocyte count seemed more valuable than the surgical procedures employed in these patients.
Authors:
R Suri; J M Goldman; D Catovsky; S A Johnson; E Wiltshaw; D A Galton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of hematology     Volume:  9     ISSN:  0361-8609     ISO Abbreviation:  Am. J. Hematol.     Publication Date:  1980  
Date Detail:
Created Date:  1981-07-23     Completed Date:  1981-07-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7610369     Medline TA:  Am J Hematol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  295-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Antineoplastic Agents / therapeutic use
Follow-Up Studies
Humans
Leukapheresis
Leukemia, Myeloid / complications*,  diagnosis,  therapy
Male
Middle Aged
Priapism / etiology*,  therapy
Retrospective Studies
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

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